Making people explode

It's been a while since I posted anything. I bought a motorbike. It's rad. However, the reason for this short missive from the 2010 is to share this delectable piece from the Huffington Post. I particularly like:

How screwed are the Republicans right now? Put it this way: the sanest contender in the above list is named "Bush." Yes, Bush: a name that proved to be even less popular this year than the name "Hussein." Yet there he is front and center.

Read it. Read it now - especially you, Foster.

Vrooom

After doing my pre-learner course last weekend with Seb, I did my motorbike license theory test today. The upshot of which is that I have a learner motorbike license. Oh. Yeah.

Picking a specialist spinner pays off

Jason Krejza has just returned the 8th best figures for a bowler on debut. Makes you wonder what would have happened if they'd picked a specialist spinner from the off. I'm happy to be proven wrong, but India still managed to compile a solid total for Australia to chase. It's looking like it could be a good Test match.

The search for a spinner

With both SMH and Cricinfo speculating that off-spinner Jason Krejza may make his test debut in the fourth Test against India, it seems the time is right to have a bit of a look at the Australian spin bowling stocks. Krejza seems an odd choice. The 25 year old has only 24 games of first class cricket to his name, with a bowling average of 50 and a relatively solid batting average of 23. However, in a game earlier in this tour of India against the Board President's XI, he returned the very unflattering figures of 0 for 199 for the match, with the figures of 0 for 76 from 11 overs in the second innings. In the Sheffield Shield last season (well done Sanitarium for giving the competition it's proper name back, by the way), Krejza took 18 wickets at an average of 47 in seven games for Tasmania. He has yet to take 5 wickets in an innings. So who else could fill the gap left by the retirement of Warne and MacGill? Let's start with the current choice: Cameron White.
White is also 25 and currently holds a Cricket Australia contract. He's a handy batsman, with a first class average of 40. His first class bowling average is somewhat less flattering, standing at 38. He became captain of Victoria in 2003/04 at the age of twenty, making him the states youngest ever captain. In 2007/08 he guided Victoria to the finals of all three forms of the game, but returned only 6 wickets at an average of 47 in Sheffield Shield. White has described his own bowling as nothing special, and his returns in the first 3 tests would seem to back this up. Interestingly, Simon Katich has a better first class bowling average (37), while Michael Clarke's bowling performance's at Test level have proved him to be a handy contributor with the ball. White is not an out and out wicket taker, and with Katich and Clarke in the team, his part time leggy's seem superfluous. As a one-day player White has a solid batting average of 26 at a strike rate of 108, with a bowling average of 30, suggesting that he may be more suited to the shorter form of the game at international level. Suitability as a replacement for Warne/MacGill: low.
Next up, another currently contracted player: Beau Casson. Casson, also 25, moved to NSW from WA after the 2005/06 season. His first class batting average is 36, while his bowling average is 41. However, his Sheffield Shield figures for 2007/08 are more impressive: 29 wickets at 35 and 485 runs at 60 made it a good season for the left armer. This led to Casson being selected for the tour of the Windies earlier this year, where he returned the respectable match figures of 3 for 129 on debut. Despite this, Krejza and Bryce McGain were chosen to go to India. Ali Cook of Cricinfo points out that the performance of Katich, especially in the third Test, is proof that Cricket Australia should have taken Casson to India. As a handy batsman and a spinner able to extract good turn, Casson would seem to be a better choice than either Krejza or White. Suitability as a replacement for Warne/MacGill: moderate.
Bryce McGain: A 36 year old, McGain struggled to get a berth in a Victorian side that boasted Shane Warne, Colin Miller and Cameron White amongst its slow bowlers. In 2007/08 he took an impressive 38 wickets at 34 - the most of any spinner in Sheffield Shield. McGain boasts a first class bowling average of 33, but his batting average is only 12. However, with Lee, Johnson and Clark all relatively handy with the bat, McGain doesn't necessarily have to contribute. The main thing that counts against him as a long term proposition is his age. While unable to play in India due to injury, he is still probably the best suited as a replacement for Warne/MacGill, but like Brad Hogg before him, he's just not going to be around for that much longer. Warne and MacGill were wicket takers, and that is what McGain appears to be too. Suitability as a replacement for Warne/MacGill: high (in the short term).
Nathan Hauritz: While Hauritz was left out of the Blues squad for the October 8 Sheffield Shield match, his performance for the Blues in the Ford Ranger Cup game that I went to on the weekend demanded his inclusion here. Defending 270-odd, the Blus got away to a horror start after Burt Cockley and Moises Enriques were taken for more than 10 runs per over each for the first 6 or so overs. Hauritz was brought on and immediately pulled the run rate back, going for 7 runs from his first 3 overs. While he didn't take any wickets, his ability to stem the flow of runs was impressive. Hauritz played a single Test for Australia in 2004, in which he returned figures of 5/103. However, like Cameron White, his figures suggest that he is more suited to the shorter form of the game, a sentiment that the NSW selectors apparently share. With first class averages of 16 and 49 for his batting and bowling respectively it would seem that a Test call-up is unlikely any time soon, but I still like the cut of his jib. In terms of filling the Warne/MacGill void he doesn't seem particularly suitable unfortunately. Suitability as a replacement for Warne/MacGill: low.
Dan Cullen: With Cullen Bailey struggling to hold onto a spot with the Redbacks, Dan Cullen has emerged as the more likely of the two to step up to the next level. After taking 43 wickets at 30 in his second summer in 2005-06, Cullen took only 18 at 49 in 07/08. He has a first class bowling average of 42 and returned match figures of 1/54 in his only Test. While Cullen has undoubtedly dropped down the list, he definitely deserves consideration. Suitability as a replacement for Warne/MacGill: moderate.
In the short term at least it seems that Bryce McGain is the most suitable replacement for Warne/MacGill, but in the longer term is has to be said that Beau Casson is probably best placed after his solid, if not remarkable debut in the West Indies. He also has the ability to contribute with the bat and is still relatively young. Still, it will be interesting to see how Krejza performs, if he's given the chance - it's likely that the selectors know more about cricket than I do...

Attribution of polar warming to human influence

A freely available article published in Nature Geoscience this week has established that polar warming is due to human activity:

Our findings demonstrate that anthropogenic influence is detectable in Antarctic land surface temperature, and distinguishable from a naturally forced response... In the Arctic, some authors have suggested that observed Arctic temperature changes are inconsistent with climate model predictions and dominated by internal variability and indeed so far no formal attribution studies of Arctic temperature change exist. We find that anthropogenic influence on Arctic temperature is detectable and distinguishable from the influence of natural forcings.

While this isn't exactly news to anyone with half a brain, it is undoubtedly an important piece of research, and a compelling counter-argument to those who say that global warming is a myth. The website of the some of the researchers who did this work, from Climatic Research Unit at the University of East Anglia, also has some interesting stuff on Climate change myths.

Huffington and puffington

I've been reading the Huffington Post lately, mainly for it's coverage of election related stuff. But I also came across this interesting article refuting the "end of days" and "America is a declining empire" argument. Foster may feel the need to point out that the writing is somewhat left-biased, to which the obvious response is "no shit".

Palin and fruit flies

Apart from a special issue in Nature, the stance of the McCain and Obama camps on science have gained relatively little air time. This is fairly disappointing, given just how broad "science" is. Global warming anyone?
However, Sarah Palin has managed to change this with her monumentally stupid comments about "fruit fly research in Paris". It would be unfair to expect a career politician to fully understand the technical aspects of modeling human disease in simpler organisms, but surely someone could explain the concept? I doubt that I can explain the issue better than Adam Rutherford of the Guardian, or even the unashamedly liberal Huffington Post writers. Words cannot describe how angry I am that it is even possible for such an ignorant fool to be anywhere near becoming the most powerful woman in the world - and we haven't even started talking about her views on climate change...

Retard jokes

What's better than winning a gold medal at the Paralympics? Not being retarded. Having set the tone of this post to "offensive", I present this beauty.

While on the subject of retards, Stu is selling a peg on Ebay. Get in quick.

The World's Second Most Inane Blog

As I was considering writing a post about how I got bitten by a tick last week, I realised that I blog about some ridiculously inane shit. I'm not the only one - the blogosphere is chock full of some seriously dull motherfuckers. Try clicking on the "next blog" tab in the top left for reassurance that you actually live a pretty exciting life. Anyway, this revelation led me to search for "most inane blog post" and "most banal blog post" on google. As such, I give you "The World's Most Inane Blog" (which actually isn't that bad) and an article about the "most banal blog ever". Now, about that tick bite...

Roy Ayers

Roy Ayers @ The Forum, Moore Park - 24th October, 2008
Originally uploaded by 'ju:femaiz

Last night I saw Roy Ayers play at The Forum. A bona fide legend of the funk, soul and jazz world, Ayers also happens to be almost 70. I've seen a few other legendary musicians who trade more on their status and past glories than their current ability (Lee Scratch Perry springs to mind), but Ayers was an absolute joy to watch, backed by an astoundingly talented group of musicians.
Joel was shooting the night, no doubt more photos will go up on his photostream in due course (photo to the right is his, I have no idea why the attribution is not showing up properly).

The More kJ Diet

I've been feeling a little bit rubbish since about last December, coinciding almost exactly with the time that I snapped my collarbone like a twig. It hasn't been anything too major, just a little bit of listlessness and a feeling of weakness when I exert myself. So I went and got a blood test a week or so ago, and the news was not good. Nothing is wrong. At all. This is not particularly helpful - I don't want to hear that I'm healthy and everything is within normal ranges, I want answers. So the doctor basically shrugged his shoulders and went "I dunno. Good luck with that."
So in order to deal with the situation I have formulated what I call the "More kJ Diet", which basically entails me eating more food. Some may call this simplistic, but I would call it elegant. More importantly, what it lacks in complexity, it appears to be making up for by actually working. If you wish to try the More kJ Diet I suggest learning the following phrases: "Are you going to finish that?", "Is there any more?", "Where the fuck did you asshats hide the bread?" and most importantly "Om nom nom nom".

On that note, I think I'll have a snack.

McCain in Rolling Stone

In my tireless quest to scour the internet for the tastiest morsels and most delectable pieces of high culture I found a piece on Citizen McCain that was published in Rolling Stone. OK, I found it on a bouldering forum. Fuck you, read it anyway.

Make-believe Maverick

Scary shit, yo.

You can also find some solid gold ranting in Mad Dog Palin.

VP Debate

So the much anticipated Palin vs Biden debate didn't end up being a gaffe-fest. Bummer. The consensus seems to be that Palin succeeded in not failing, while Biden managed not to appear too condescending. Here's an interesting youtube video comparing how the two VP candidates dealt with exactly the same question in an interview:



Fairly conclusive really. Regardless of her politics, she really shouldn't be out in a position of power. Hopefully the people who actually get to vote on it see this.

Flavours

Alright, I haven't even read over this yet, so if you wish to point out pedantic grammatical errors you can go and get fucked. Otherwise, enjoy:

Yeast organoleptic compounds

Overview

The organoleptic (or flavour) compounds produced by yeast can be divided into five categories: alcohols, esters, aldehydes and ketones, sulphur-containing compounds and acids (Berry and Watson 1987; Verstrepen et al. 2003c). Yeast can also affect flavour by altering compounds already present in the substrate (e.g. wort or must)(Berry and Watson 1987), but it is those compounds produced as a by-product of yeast metabolism that are of most interest here.

Flavour thresholds

The absolute amount of a compound is not the most important determinant when evaluating its influence on flavour, as different compounds have different odour and flavour thresholds. A low flavour threshold means that the compound is detectable at low concentrations, while a compound with a high flavour threshold must be present in large amounts to be detectable (Berry and Watson 1987). However, even if a compound is present at levels below its flavour threshold, it can still affect the flavour profile through synergistic interactions with other compounds (the so-called “matrix effect”)(Meilgaard 1975). Further, some compounds are desirable at low concentrations, but undesirable in large amounts. Ethyl acetate, for example, imparts a “fruity” aroma at low levels, but is described as “solvent-like” at high concentrations (Verstrepen et al. 2003b; Swiegers et al. 2006).

Aldehydes and ketones

The majority of the flavour-active aldehydes and ketones result from chemical reactions in the pre- and post-fermentation stages rather than as a direct result of yeast metabolism. An exception is pyruvate, and to a lesser extent a-ketobutyric acid, which both influence the mouth-feel of beer and wine(Berry and Watson 1987). Acetaldehyde is another important flavour-active aldehyde synthesized by yeast. It has an apple-like and nutty aroma, and can affect the colour of red wines. It is rarely present in beer or wine at values above its flavour threshold (Berry and Watson 1987; Swiegers et al. 2006).

The vicinal diketones, 2,3-butanedione (also known as diacetyl) and 2,3-pentanedione are very important flavour compounds with very low flavour thresholds. However, they are formed by a non-enzymatic reaction that takes place outside of the yeast cell. This conversion of a-acetohydroxy acids released by yeast cells is an oxidative decarboxylation that is enhanced by the presence of oxygen (Swiegers et al. 2006). Yeast is involved in the enzymatic reduction of these compounds into the corresponding 2,3-diols, however (Berry and Watson 1987).

Sulphur-containing compounds

Sulphur-containing compounds are usually present in very small amounts, have low flavour thresholds, and are often associated with negative flavour descriptors such as cabbage, rotten-egg, sulphurous, garlic, onion and rubber. They fall into five major groups: sulfides, polysulfides, heterocyclic compounds, thioesters and thiols(Swiegers et al. 2006).

The major flavour-active sulphur containing compounds, sulphur dioxide and hydrogen sulphide, are formed as by-products of cysteine and methionine biosynthesis from inorganic sulphate, and can also be formed during the degradation of these amino acids. Many sulphur compounds are formed by the interaction of yeast with hop compounds in brewing, and pesticides and other sulphur containing compounds found in grape must in winemaking (Berry and Watson 1987; Swiegers et al. 2006). While associated with negative flavours, sulphur dioxide is often considered desirable in beer and wine due to its anti-oxidant and anti-microbial properties (Yoshida et al. 2008).

Organic acids

Organic acids produced by yeast are derived from three areas of yeast metabolism; those derived from the breakdown of pyruvate, those derived from the breakdown of certain amino acids via the Ehrlich Pathway (the fusel acids) and those produced from malonyl-CoA by the fatty acid synthetase pathway (Berry and Watson 1987; Hazelwood et al. 2006; Saerens, S. et al. et al. 2008). It is rare that the acids derived from the breakdown of pyruvate are present in concentrations even close to their flavour thresholds, with the exception of acetic acid. These acids can affect the mouthfeel of beverages however, and also affect the final pH. 2006; Hazelwood

Fusel acids

The breakdown of certain amino acids, including leucine, isoleucine, valine, methionine, tyrosine, tryptophan and pheylalanine, involves a sequential transamination and decarboxylation. The resulting aldehyde can then either be reduced to an alcohol or oxidised to form an acid in a process referred to as the Ehrlich Pathway (Vuralhan, Z et al. 2005; Hazelwood et al. 2006; Hazelwood et al. 2008). The fate of the aldehyde depends on the redox state (essentially the oxygen availability) of the cell (Vuralhan, Z. et al. 2003). Fusel acids (and alcohols) may also be synthesized from a-keto acids derived from the pathway used by the cell to produce amino acids (Berry and Watson 1987). Unlike higher alcohols which freely diffuse across the cell membrane, organic acids are actively transported out of the cell by Pdr12p (Hazelwood et al. 2006).

Short and medium chain fatty acids

This is the major class of acids produced by yeast. In terms of flavour they are important both in their own right and, in their activated form, as precursors in the synthesis of ethyl esters (Berry and Watson 1987; Saerens, SM et al. 2008a). In Saccharomyces, malonyl-CoA is synthesized by Acc1p, a biotin-dependent acetyl-CoA carboxylase. Malonyl-CoA is the substrate for the fatty acid synthase subunit (FAS), encoded by FAS1 and FAS2. This complex is responsible for the production of saturated fatty acids, including palmitic (16:0) and stearic acid (18:0). However, during alcoholic fermentation short and medium chain fatty acids, including hexanoic (caproic, C6) acid, octanoic (caprylic, C8) acid and decanoic (capric, C10) acid may be prematurely released from the FAS complex. (Berry and Watson 1987; Furukawa et al. et al. 2008a). It has been known for some time that these compounds are produced via this route rather than via b-oxidation of longer chain fatty acids(Taylor and Kirsop 1977). Further, Furukawa and co-workers showed that altering the expression of FAS1 and FAS2, by both overexpression and by inositol-induced downregualtion (mediated by the transcription factor OPI1) affected levels of both medium chain fatty acids and ethyl esters (Furukawa et al. 2003). 2003; Marchesini and Poirier 2003; Saerens, SM

Alcohols

While some 45 alcohols have been identified in beer, ethanol, n-propanol, isobutanol, 2-methyl-1-butanol (amyl alcohol), 3-methyl-1-butanol (isoamyl alcohol) and phenylethanol are the most important from a flavour perspective (Berry and Watson 1987; Verstrepen et al. et al. 2006). While other alcohols such as glycerol can affect the mouth-feel and apparent sweetness of a beverage, the so-called “fusel alcohols” or higher alcohols are the flavour compounds present in beer and wine at the highest concentrations (Verstrepen et al. et al. 2006; Hazelwood et al. 2008). At high concentrations, higher alcohols are associated with solvent-like off flavours but are desirable at lower concentrations. Phenylethanol in particular imparts a floral, rose-like flavour and is particularly desirable in white wines(Berry and Watson 1987; Swiegers et al. 2006). Ethanol is a precursor in the synthesis of both ethyl esters and ethyl acetate, and the fusel alcohols are precursors in the synthesis of acetate esters (Verstrepen et al. 2003b; Saerens, S. et al. 2006; Swiegers et al.. 2003c; Swiegers 2003b; Swiegers 2006)

The Ehrlich Pathway and higher alcohol synthesis

The majority of the alcohols produced by yeast are products of the breakdown of amino acids via the Ehrlich Pathway. German biochemist Felix Ehrlich first noticed the similarity between leucine and isoamyl alcohol in 1904, and proposed that amino acids were split by a “hydrating” enzyme to form the corresponding fusel alcohol in 1907(Hazelwood et al. 2008). The classical Ehrlich Pathway as it is viewed today was proposed by Neubauer and Fromherz in 1911, and involves a sequential transamination, decarboxylation and reduction. Recently the formation of fusel acids resulting from the oxidation of the fusel aldehyde has been included in the pathway (Vuralhan, Z. et al. 2003; Hazelwood et al. 2008). The amino acids broken down via this pathway include leucine, isoleucine, valine, phenylalanine, tryptophan, tyrosine and methionine. Table 1 shows the products of the breakdown of these amino acids.

Fusel alcohols may also be derived from the pathway responsible for amino acid biosynthesis. In this situation the a-keto acid made by the cell for amino acid biosynthesis is decarboxylated and reduced to the corresponding amino acid. Propanol is produced solely by this mechanism, and is not derived from the breakdown of threonine (Berry and Watson 1987; Saerens, S. et al. 2008b)

Esters

Volatile esters synthesized by yeast that are found in beverages can be divided into two groups. Ethyl esters are synthesized in a reaction catalysed by Eeb1p and Eht1p from ethanol and medium chain fatty acids (Saerens, S. et al. 2006). Acetate ester synthesis is catalysed by the alcohol acetyl transferases Atf1p and Atf2p (and LgAtf1p in lager yeasts) from acetyl-CoA and higher alcohols. Because acetate ester synthesis requires an activated substrate, a process which consumes ATP, it is considered to be an energy requiring process (Peddie 1989; Mason and Dufour 2000). The fact that it also consumes acetyl-CoA, an important precursor in lipid synthesis, amino acid synthesis and the TCA cycle (among others), has led some researchers to suggest that acetate ester synthesis is not a futile process (Verstrepen et al. 2003a). Over-expression of the ethyl ester synthesizing genes has no effect on the amount of ethyl esters produced, while over-expression of ATF1 and ATF2 results in a significant increase in the formation of these acetate esters. From this it was concluded that in ethyl ester synthesis substrate availability was the determining factor, but in acetate ester synthesis it is the activity of the enzymes responsible that determine the amount of esters produced (Verstrepen et al. et al. 2006). Increasing substrate availability will also lead to an increase in acetate ester synthesis, but this has a much less pronounced effect than the over-expression of the alcohol acetyl transferases (Verstrepen et al. 2003b). 2003b; Saerens, S.

Ester levels may also be affected by the action of esterases. Both Eeb1p and Eht1p have been found to have ethyl esterase activity (Saerens, S. et al. 2006), while Iah1p (Isoamyl acetate hydrolysing enzyme) has esterase activity against acetate esters (Fukuda et al. 1996). It has been suggested that final ester concentration is a result of the balance between ester synthesis and the action of esterases (Fukuda et al. 1998).

Something weird happened to some of the reference formatting when I copy pasted it - sorry about that.

Reviews all up ins

Some sounds that have been in my ears recently:
Calypsoul 70 - Caribbean Soul 1969-1970

Brownswood Bubblers vol. 3 - compiled by Gilles Peterson

and the astoundingly good new Hermitude album, Threads.
("Check out the tracklisting" is not mine, btw).
Hermitude are touring with Horrorshow, but unfortunately the Sydney show clashes with Roy Ayers. On the upside, I'm going to see Roy Ayers!
While on the topic of music, check this out - Cyclic Selects: Paradise Lost

And I'm spent.

Python vs Hippo

For some reason we were talking about snakes in the lab yesterday. I'm not sure exactly how this led to us watching snake videos on youtube, nor why we chose this one in particular, but I think the fact that it's called "Python vs Hippo" may have played more than a small part.



Almost as awesome is "Cobra vs Python"



I told Tom about these, and he passed on "Pelican eats pigeon"



What did people do before youtube? All this crazy stuff was out there and no one got to see it. Three cheers for the interweb! Three cheers for technology! Most of all, three cheers for Friday afternoon.

Ska!

The sweet thing about having a 160 gig ipod is that I can fit a shitload of music on there. Like, heaps and heaps. So I've been ripping some of the better ska records from my absurdly large collection of cheesy ska. In the process I've rediscovered The Planet Smashers, The Toasters and the Gadjits, as well as The Australian Ska Orchestra. It would appear that the Australian Ska Orchestra is no longer around, at least not in the form that it was in when they recorded "Storm Warning" and "Rainy Night in Horsham" (released on File Under Ska vol. 2). I did, however, discover the Melbourne Ska Orchestra, who suck only moderately. I also have a ridiculous amount of CD's that are, and only ever were, complete and utter rubbish. One example is Ruskabank, who against all reason, are apparently still around. Ha, check this shit from their website:

Warning:
Some of the features on these pages such as the Scroll Bar and Text Formating style sheets, may not work if you are viewing on a Mac. The site was created on a PC and optimized for viewing on IE 5.0 or later. Also, Firefox doesn't display the scroll bars properly.

Classic. I can practically feel Joel's rage from here. He's all "@Ruskabank: You IDIOTS!!!!!11". Unfortunately the fact that I paid money for their music also fills me with rage.

Introduction

Here is a very small excerpt from the first draft of the introduction to my thesis. Despite the fact that my PhD. is being paid for by a large brewing company, I'm not a brewing expert per se. Maybe you'll find it interesting, maybe you'll give some feedback.

The Brewing Process

History

The brewing process is thought to have been developed some 6000 years ago by the Sumerian people of Lower Mesopotamia (Hough 1985). The fermentation process helped make normally undrinkable water more potable by lowering pH and increasing alcoholic content, thereby reducing the number of potentially harmful bacteria and increasing the nutritional value, especially in beverages in which the yeast was still present (Hough 1985). As brewing spread into Europe, the addition of hops was added to the process, improving both flavour and aiding preservation (Hornsey 1999).

Malting

Malting is the process whereby cereal grain (usually wheat or barley) is germinated in order that an enzymatic degradation of the grain’s endosperm may occur. This process makes sugars and other cellular components easily extractable from the malt. Once this germination has taken place, the grain is kilned to reduce water content and increase the activity of proteases and amylases. The malt is then milled to produce smaller particles known as grist, which are more accessible to enzymes later in the process(Hough 1985).

Mashing

The grist is placed into a large vessel known as a mash tun, and hot water is added until a porridge-like consistency is reached with a temperature of 55-65°C. Insoluble malt extracts are removed by filtration, and the resulting mixture is referred to as wort. The wort is then boiled in order to sterilize it, and to stop any enzyme activity. Hops are then added to enhance flavour and aid in preservation of the finished product (Hornsey 1999).

Fermentation

During fermentation the sugars in the wort are converted to alcohol by the metabolism of yeast. The process begins when a vessel filled with wort is pitched (inoculated) with yeast at a concentration of approximately 300g hl^-1 (Hornsey 1999). It is important that the fermenter is aerated at the beginning of the brew, as pitched yeasts often contain low levels of the essential membrane sterol, ergosterol (Aries and Kirsop 1977). Synthesis of both ergosterol and the essential unsaturated fatty acid oleic acid require oxygen (Andreasen and Stier 1953). Once fermentation begins, cell density rapidly increases and anaerobic conditions are established, and sugars are fermented to ethanol via the Embden-Meyerhof-Parnas pathway (Hornsey 1999). Once fermentation has ceased, the green beer (beer that has not been aged) is removed for maturation, clarification, satabilisation and packaging (Hough 1985; Hornsey 1999).

There are many factors during this process that can have a profound effect on yeast metabolism and the flavour profile of the final product. These include the sugar and amino acid content of the wort, brewing temperature, availability of metal ions such as zinc and the size and shape of the fermenter (Berry and Watson 1987; Verstrepen et al. 2003a; Swiegers et al. 2006).

I'll post the stuff about flavour compounds a bit later.